As the title says: please comment your successes with Letrozole!

28F with lean PCOS TTC for 6 months. Did a paid referral to a fertility clinic and now have NHS funded treatment. Waiting for my Provera and Letrozole prescription to come through. My first cycle will be monitored with timed intercourse (husband semen analysis was normal - just slightly high viscosity).

I've gone down a rabbit hole of looking at success rates and spiralled into thinking there's a massive chance it doesn't work and after 6 cycles I'm going to be put on an IVF waiting list.

I take 4000mg inositol (in the correct ratio) alongside fish oil, magnesium glycinate and prenatal supplements. Also doing carb pairing, 8k steps daily and post-meal walks. This foundation hasn't helped me ovulate regularly but hoping it will help letrozole success

Hi! I'm sure this has been asked before but I'm looking for advice for my situation. We are doing medicated cycles and are taking a break for a few months if this cycle is unsuccessful and looking for advice for what to do while we take a break. I'd give anything to be able to try naturally while we take our break from treatments. At this point, I've just about given up on being able to have a cycle at all but wanted to just try one last time to see if anyone has advice!

I've been TTC for almost a year and got diagnosed with pcos this year but have had symptoms & problems for 15 years. I'm currently on my 3rd medicated cycle, which has been successful with making me ovulate but no success with pregnancy yet. Without meds, it's like I don't have a functioning reproductive system at all. I have an extremely high AMH of 28 ng/ml. Ovaries blocked with follicles. I don't have periods, ever. I don't ovulate, ever. I didn't appear to ovulate in my life until my medicated cycles this year.

I'm currently taking inositol 4000mg daily. I was on it for about 5 months without any luck regarding my periods or ovulation. I know they say give it 6 months but I began medicated cycles at 6 months, so idk if it worked. And then all of my metabolic markers are normal. My hormonal bloodwork is normal outside of my AMH and my LH is 1.8x higher than my FSH. I strength train and eat as well as I can. So I guess I'm just not really sure what else to do. Nothing I seem to do makes any difference.

TIA!

hello!

my husband and i have been TTC for a year. 3 months ago i got my progesterone drawn at 7dpo and it was 2.3. cycle after that i started letrozole 2.5 and got a progesterone drawn at 7dpo. it was 4.6. this month we did 5 of letrozole and progesterone suppositories starting at 2dpo. got my labs drawn at 7dpo and it was 23.2! went to see my fertility doctor yesterday and she was very pleased with my levels. she thinks we could be pregnant now. i don’t wanna get my hopes up but anyone else have a similar experience?

PS im 12dpo today:)

I normally have a 35-40 day cycle but recently had a 29 day cycle for the first time.

Hi everyone, first I want to say how grateful I am to have found this community, it’s given me so much reassurance and comfort over the past few months.

My situation: 33 years old, married, ttc and newly diagnosed with pcos in July. Obgyn said it’s probably been masked by BC for years. My AMH over is 16, A1c is 5.3, horrible cystic acne, unexplained weight gain, fatigue, the works.

Last month we did our first round of letrozole 2.5 with timed intercourse (unsuccessful) and my dr recommended we go straight to RE because of low motility results (3%) in husbands SA.

My questions: I’ve been taking inositol, working with a nutritionist and incorporating more strength training since July and have not lost any weight or seen any improvements in my cycle or ovulation. Is it worth going on a glp1 for a couple of months while I wait for my RE appointment in mid-December? Any other recommendations? The uncertainty is so hard to manage.

Using 5mg letrozole day 2-6, I had a scan on day 13 I had 2 mature follicles and told ovulation was imminent.

Day 14 in the evening my LH test was positive I took that as my surge, day 15 really strong ovulation pain, EWCM and BD both those days.

The problem is my LH tests seem to always linger around 0.7 even after my peak and yesterday day 17 I got another positive test, I’m 95% sure I DID ovulate on day 15 but now I feel like I’m unsure and should be trying again incase I miss it. However I’m taking progesterone suppositories and also feel so tired in general from the whole process.

Any advice on if I keep trying or trust the first surge?

Also I am not tracking BBT - I should but I forget more often than not and need to buy a new thermometer

got my pcos diagnosis two months ago and we officially started trying this cycle. i've been reading this sub nonstop and i'm kind of drowning. some people temp, some use three kinds of strips, some are doing bloodwork every week and i don't even know what half the acronyms mean yet

my cycles are anywhere from 38 to 80 days, last one was 74, so period app predictions are basically useless. my husband also wants to actually be part of it instead of me just texting him "tonight" every few days

if you were starting over, what would you track first and what would you skip?

I can't help but feel like im in a unique situation because I've never came across someone else with a similar story to mine.

September 2024 I got my mirena coil removed. By December I got my first period and it was... an experience. Lets just say if we were bleeding from anywhere else in our bodies like that, we would be in ED.

By approx April 2025 I had went from the occasional spotting that gradually increased to spotting/bleeding everyday. Some days were like a period while other days were minimal spotting when wiping.

September 2025 I seen a doctor who said this was due to my pcos. I asked for a second opinion. In October 2025 I was told i would need a hysteroscopy and in February 2026 I was told they found a benign poylp which they removed but ruled out hyperplasia. I raised my concerns regarding endo and was told due to my bmi they would not do a lapraoscopy but they would do a abdo/pelvic mri which ruled out endometriosis. In march 2026 I started oral provera 10mg everyday for initially 3 months. By the end of the 3 months I had only just stopped spotting by 2 days so I was told to stay on it for another 3 months. I finished that at the end of September and have since had a couple of episodes of spotting lasting a few days and my first period. I am back to tracking ovulation and I think yesterday for the first time ever it shows a rise in LH. I know these tests can be unreliable for women with pcos so im also tracking bbt (no pattern/spike noticed) and cervical mucus (the provera caused a lot of dryness but while i havent got the egg white consistency yet i think things are starting to make progress there too).

Im currently trying to lose weight for fertility treatment also. My bmi has went from 42.6 to 30.9.

Has anyone had any similar experience? My doctors were hopeful if I lost weight id be able to conceive naturally. Has anyone been able to conceive naturally after weight loss? Ill be honest, my docs focused so much on losing weight they've almost convinced me that it will 100% happen if I lose more weight (although i know that may not happen)

I’m 33F with PCOS and currently TTC. My last two cycles have been regular (29 days).
I’m currently on CD22. I had my progesterone tested on CD21, and it came back at just **1.3 nmol/L**, which seems very low for the luteal phase.
However, my Oura temperatures have been rising for the past two days (+0.1°C and +0.2°C), and today Oura flagged “Major Signs of Strain” despite me feeling completely normal.
I’m confused about whether I’ve already ovulated, might be ovulating late, or haven’t ovulated at all.
**Has anyone experienced low progesterone around CD21 but confirmed ovulation later? Can temperatures rise even if ovulation hasn’t happened?**
Would really appreciate hearing your experiences, especially from anyone with PCOS!