r/PetMice • u/MangoTheQuirkyCat • 7h ago
r/PetMice • u/ArtisticDragonKing • Sep 22 '24
Care Guide Series Community Care Guide
This post is mouse care simplified, for beginners! It is not very specific, and it does not cover everything, so please do not rely on just this post when educating yourself on mouse care!
This has been written and discussed by moderators of the subreddit. If you have questions or concerns, please comment to let us know! It will be updated regularly to ensure it is factual.
1. Mice are social!
- Females always need other female companions. It is recommended to have at least 3, but 2 is okay.
- After 6 mice in one cage, it is often they will start to split up and become territorial against the opposing group. It is suggested to keep your colony under 6 unless you have much knowledge and experience, OR if your mice are littermates.
- Males can not be housed with other males ever! If you want them to have cage mates, neutering (very risky) and placing with females or leaving intact and bonding with ASFs (African Soft Furs) is beneficial and recommended. Otherwise, they can thrive in solitude.
See this post for more information.
2. Cages
In mouse communities, many users go by tank size rather than listing dimensions. We will do both!
- 10g/20x10 inches is no longer suggested for mice.
- 20g/30x12 inches is suitable for 2-4 females or 1 male, but it's highly suggested to aim for 40g or larger.
- 40g long/36x12 inches is suitable for 2-5 females or 1 male
- 40g breeder/36x18 inches is occasionally suitable for 2-6 females or 1 male
- Over 40g is not always suitable for any amount of mice since many mice do better in environments with less open space. Bigger is only better with thorough clutter and certain colony sizes.
Any amount of mice may thrive in larger enclosures than suggested above. However, it is critical that the larger the enclosure is, the more clutter provided, otherwise the mice will never thrive.
- Wood enclosures are suggested against since urine will effect its quality and smell over time.
- Mesh flooring is dangerous due to the chance of toes/tails getting caught, the mesh cutting their skin, and risking bumplefoot. Mesh should also be avoided in wheels.
- Though they climb, mice don't need very much height, and multi-story enclosures do not provide them with the proper space they need. Floor space is more important than height.
- Cages with lots of attachments and rooms do not provide proper space for mice. They are also extremely difficult to clean, fall apart easily, and struggle to hold proper bedding amount and safe wheels.
See this post for more information.
3. Substrate
- Mice need to be able to create burrows, so while the minimum is 6 inches, we suggest at least 8" of bedding. However, many owners prefer having 10-12" deep!
- Bedding must be majority safe wood shavings or hemp. Paper substrate does not absorb ammonia well and can cause several health issues when used alone or as majority of substrate.
- (Dust/scent free for all) Aspen, kiln dried pine, and hemp do well as the main substrate and may be more sturdy mixed with a small portion of hay or paper bedding.
See this post for more information.
4. Clutter
- Clutter is arguably one of the most important aspects of a mouses cage. No matter the size, if the cage lacks clutter, it is not suitable.
- Toilet paper rolls, cardboard boxes, tea light and soap dish ceramics, rodent hideouts, branches, logs, cork bark, cardboard egg cartons, and much more can be used as clutter in the cage.
- From a birds eye view, you should be able to see little to no bedding. While it may seem too cluttered to a human, it's perfect for mice!
- The larger an enclosure, the more crucial clutter is.
See this post for more information.
5. Enrichment
- Also known as entertainment, to keep the mice busy!
- Boredom breakers, foraging toys, dig boxes, sprays(plant), scatter-feeding, and human interaction are all forms of enrichment.
- Mice should have boredom breakers in their enclosure at all times to keep them from growing bored.
- Lone males need extra simulation and enrichment.
See this post for more information.
6. Climbing Opportunities
- A form of enrichment that is required!
- Mice flourish with climbing opportunities and will always take advantage of them.
- Ropes, bird ladders, hanging toys, rope nets, shower curtain rings, and bird perches are a few climbing options you can provide.
- Fabric hammocks are used commonly, but pose a threat when chewed on and loose strings get tangled around limbs. Minimal use of fabric is suggested for this reason.
See this post for more information.
7. Exercise
- A form of enrichment that is required!
- An upright, solid wheel of 9 inches in diameter or larger must be provided at all times. 2 or more are suggested for groups of girls.
- Spinning saucer disks or hamster balls/cars are UNSAFE and should never be provided, no matter how much you think your mouse may enjoy it (fun≠safe)
- Proper wheel brands may include Niteangel, Silent Spinner Exotic Nutrition, Oxbow, Wodent, Bucstate, and Trixie (but there are many more besides these!)
See this post for more information.
8. Diet & Hydration
- Main diet must be pellets/lab blocks.
- A high variety food mix (nuts, seeds, grains, ect) must be given 1-3 times a week, or even as long as once every two weeks. The frequency is owner preference.
- Feeding is 3-5 grams per mouse a day.
- Ensure your mice have constant access to food through toys and scatter-feeding.
- Food bowls are suggested only for fresh fruits or veggies since they provide no enrichment otherwise!
- Mice must have at least two water sources and constant access to them at all times. Bowls or bottles work well, though having one of each is ideal. Water must be cleaned and refreshed daily.
See this post for more information.
9. Cleaning
- Daily spot checks to clean up mess, poo on toys/clutter, and urine on the surface is vital.
- Bedding changes will be needed less often with more bedding and space. A 10g tank (or cage of similar size) would need weekly bedding changes.
- Each enclosure size and mouse amount will effect how often bedding changes are necessary. Find a cleaning schedule that ensures the cage doesn't smell at any time for your mouses health.
- With deep bedding over 6 inches, you'll have to change out less of the bedding. 1/3 to 1/2 of the bedding may stay in the enclosure while the most soiled areas are removed and replaced.
- In any case, a small amount of bedding must be left over after a bedding change to decrease stress.
See this post for more information.
10. Taming
- Allowing your mice to settle in for a few days before interacting with them is wise.
- Rub your hands on bedding and toilet paper in the cage to get the mice used to your scent.
- Encourage interaction through hand feeding.
- If a mouse is not motivated to interact after several weeks, try to lure them to climb onto your hand for treats. A strong bond is important with mice so they are well adjusted to interaction in case of a vet visit or emergencies. Human interaction can also be beneficial to them.
See this post for more information.
11. Other
- Mice are crepuscular and are typically seen during the morning or late day/night.
- They are self bathing and should never be washed with water or soap (unless vet prescribed). It ruins the health of their fur coat and leaves them more susceptible to URIs and freezing. They do not need any form of bathing/washing.
- Mice don't hibernate. If a mouse appears to be in a hibernation state, this is Torpor, caused when they overheat or freeze. This is a medical emergency.
- You should never pick up a mouse by its tail or other limbs.
- Fancy mice (aka domestic mouse) live 1-2 years on average.
- Wild mice do poor in captivity, unless they are unfit for the wild they should not be kept as pets.
- You should never breed mice purposely without years of research and mouse owning experience prior.
- Vet visits are a likely occurrence in mouse ownership, since mice are prone to many health issues.
- Travel carriers are needed for vet visits, emergencies, cage cleaning, and quarantine.

12. Links & Other Posts
Shopping
In Depth Mouse Care
- Taming & Holding Mice
- Social Tendencies & Proper Intros
- Enclosure Size & Requirements
- Cleaning & Sanitation
- Carriers & Quarantine (coming soon)
- Clutter & Climbing Opportunities
- Exercise & Enrichment
- Bedding & Substrates
- Diet & Hydration
- Safe Food List
- Safe & Unsafe Products (coming soon)
- Health & Signs of Illness
- Catching an Escaped Mouse
- Owning on a Budget
Other Species
Up-to-Date Posts From NotApplicableMC & Others
- How To Hand Rear a Baby Mouse
- What To Do With a Wild Mouse
- Wild Mice are Poor Pets
- First Aid Information
- Pain/Illness Charts
- Mice Are Not For Kids
Outdated Posts From NotApplicableMC
These guides are incredibly thorough and well written. However, they link some information that is no longer available, or they list mouse care information that has been dis-proven. An important point to make is these guides may suggest some controversial topics, most of which our community does not fully support. Although these guides don't follow our standards exactly, they are still very well made. Please keep an open mind and read all sides of a controversy before deciding which you feel works best for your mice.
- Male/Female? & Housing
- Bedding/Substrate and Cage Supplies/Items
- Cleaning and Food/Diet
- Sourcing mice, Taking home, Re-homing, Escapes, and Playtime
- Introducing/Socializing, Taming, and Behaviors
- Health and First-time Buyers Checklist
- Owning on a budget
I have decided to share these because they are very descriptive on some aspects of mouse care I did not cover well. I strive to have a guide in the future as well made as these, but for now, I have to bring attention to the effort made by this member.
Scientific Studies
- Sources & Additional Articles (coming soon)
- Safe & Unsafe Foods Sources (coming soon)
More community resources coming soon
r/PetMice • u/ArtisticDragonKing • Jul 09 '25
Community Help Temporary Post for Care Commands
Please feel free to try out these WIP care commands in the comments! Let me know if there are any issues I need to fix.
r/PetMice • u/Josephinedavis • 14h ago
Cute Mouse Media The way the grasp and savor their food is just so precious 🥺
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r/PetMice • u/mrbleeh • 1h ago
Cute Mouse Media The girls having "icecream"
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My mom.got my bunny this as a treat and rabbits cant have seeds- so the girls got a surprise treat instead 💖
r/PetMice • u/Educational-Use-6250 • 18h ago
Cute Mouse Media sleepy critter
little fella just waking up, felt like sharing because hes quite possibly worlds cutest mouse
r/PetMice • u/Negative-Lifeguard74 • 10h ago
Question/Help Is my mouse pregnant?
I’ve only had hamsters and after my last one passed i decided to to get mice instead so I got her a week and a half ago as well as 4 others. they’ve been establishing their territories and she’s the biggest so she’s been chasing everyone around but it’s calmed down the last few days. i don’t know if this is because she’s pregnant or because it’s a new environment. she’s pretty shy so these are the best pictures i can get of her but i can’t tell if she’s pregnant or just a bit fat.
r/PetMice • u/Sternfritters • 1d ago
Cute Mouse Media Insane posture my man
She looks like a fortune cookie 😭 now I see how mice get into everything
r/PetMice • u/_humanERROR_ • 5h ago
Question/Help Neutering soon. Forgot to ask vet this.
I'm getting my boy neutered soon so that he can have female companions and stink less. Cause otherwise he doesn't like me and would be quite lonely.
I forgot to ask the vet if I should discourage activity during early recovery by for example taking away climbing stuff. He told me that recovery would be quite straightforward but I would worry about my nouse accidentally or non-accidentally ripping the suture site.
r/PetMice • u/longleggeddoll • 6h ago
First Time Owner female mice fighting?
Hi everyone,
I’ve just gotten two female mice and one of them keeps fighting the other. They were raised together. I maybe got them 20 minutes ago, and they’ve fought twice. Just wondering if this behavior is normal or not, as I want both of them to be safe. I saw no blood, but they were biting each others’ backs and squeaking. Now one mouse is secluded to one side of the cage and has not moved since.
Would getting another mouse help this dynamic? Is this normal behavior?
Please help 🥲🙏
Edit: they’re in a Niteangel enclosure (40 gallons)
r/PetMice • u/CucumberEasy3243 • 1d ago
Cute Mouse Media this is a bug - a thesis
smol ✅ poor eyesight ✅ loves hides ✅ more than 4 limbs ✅ long sensitive feelers ✅ will walk all over you ✅ leaves tiny poop everywhere all the time ✅ can live happily in a terrarium ✅ adorable ✅ I could go on but it's pretty clear to me
r/PetMice • u/Justpeachyyyx • 7h ago
First Time Owner First time mouse owner
I’ve had hamsters, rats, guinea pigs but never mice.
I have things coming on Thursday
Cage 105cm x 51cm x 53cm
Two different kinds of substrate
Food
Sprays
Hides
Rope
Forrage mixes
Bowls
I still need to get
Meddow hay
Cork bark
More hides
Wheel - what’s the best size for mice?
Am I missing any essentials (UK)
r/PetMice • u/Warm-Addition-6181 • 19h ago
Question/Help Red spots/scabs on tail
Hey guys, anyone have experience dealing with this or know what these red spots/scabs may be? I just noticed them crop up suddenly on my 2+ year old girl Oreo. TIA
r/PetMice • u/MooseyMitch • 1d ago
Setup Tour My mouse tank
Just wondering what everyone's thoughts might be on my mouse tank. I've had two girl mice for the past 2months roughly. Pretty new to this. Feel free to leave a suggestion or ideas.
r/PetMice • u/MangoTheQuirkyCat • 1d ago
Cute Mouse Media My girl Opal turns two year old tomorrow!! She’s doing amazing, shows so signs of slowing down, and still eats and runs around with her friends every night!
r/PetMice • u/General-Childhood963 • 1d ago
Cute Mouse Media fresh new home!!
kind of a follow up if you saw my post about grain/mold mites on our tank a few days ago. also just cute pics.
my boys got an entirely new setup and they're loving all their new chew toys and play things (particularly the giant wheel they have now.) my little escapee who tried to disappear during transfer TWICE is actually the one loving it the most. silly how that works. we're still dealing with mites, but less and less every day. just glad my babies are happy and healthy!
if you read this far, i still have a baby with no name. help me pick! so far i have matcha, moose, and carrot cake. nothing has stuck for the other one 🫠
r/PetMice • u/stupidgayghost • 1d ago
Cute Mouse Media nimbus photo dump
cause he gotta go to the vet for the 4th time bc his eye keeps getting irritated
edit: GUYS IGNORE MY DOG IDK WHY THAT GOT ADDED OH MY GOD
r/PetMice • u/Lovesickmikan • 1d ago
Discussion “As quiet as a mouse”
lol ok I always think of the phrase as quiet as a mouse, because my boy is anything but quiet when he’s up! Does anyone else have a really loud mouse? What do you think about this phrase? Anyways this is just funny because as I’m writing this he’s banging the wheel on the side of his cage to dig under it 😭
r/PetMice • u/RaspberryEmma • 1d ago
Cute Mouse Media Wanda just gave birth for his 7 little kidos
r/PetMice • u/CLOWTWO • 1d ago
Cute Mouse Media Coco and her mama Olive!
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Many of you love Coco and her big ears so I'm sure you'd appreciating seeing the mouse who brought her into this world :)
r/PetMice • u/sunflowerlacroix • 1d ago
Question/Help Strange behavior
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I got this mouse from my niece a couple of months ago. He is around 3 years old.
The last two days, he has been out more than usual and looking around. Earlier today, he was sitting at the highest point of this cage and was squeaking loud enough that I heard it over the TV. He did it two or 3x.
This is him now. He is sitting at the high point again and he sounds maybe congested? He is very lethargic too but he’s eaten normally. Any advice?
I can see if my vet takes nice but I honestly don’t know. I’m new to this and it’s freaking me out lol.