Need ko parin po ba mag take ng PrEP kahit partner ko yung ka s*x ko?

Hi, today is day 8th im taking Descovy, i missed a does on day 5th. Am i ready for anal sex?

Sorry for asking this here, im getting preps from mistr and they are not responding to my questions. Thank you.

Hi everyone! Been taking truvada daily for the last 6 months approx. On my last general bloodwork hepatic enzymes alt and ast came back slightly increased from normal levels. Normal ggt. Negative hepatitis a,b,c tests, normal liver echo. No signs of other infections.

Stopped truvada for a month to check the enzymes again.

Has anyone had similar experience with truvada?

Anyone here on United Healthcare and taking Apretude or Yeztugo? My employer is switching to UHC next year and it seems like they don't cover these drugs, but I'm having trouble believing that is true.

got yeztugo injections, one on each thigh.

First injection barely felt a thing, only felt pain as the medicine was filling up.

Second thigh felt immediate burning that got worse as it filled up and didn’t go away. Got it over an hour ago and the burning is still incredibly severe- I can’t think about anything else. I don’t know why one side would be so dramatically more painful than the other.

it also feels (and looks) like its spreading out on the second thigh. The second thigh almost has vein like streaks.

just worried and want to know if this is normal, and really curious what could have happened on the second thigh. If the burning doesn’t go away, what should I do?

Hey all, sorry second question in quick succession about prep. Heading to a HIV prevalent country for work end of next week.

Will begin starting prep today and see how things go and fingers crossed no side effects.

If all good just curious if I’m out having a good time having a few too many drinks does this affect anything??

Prep will only be for a short time due to trip for my peace of mind.

Hello,

I understand these might be annoying, but genuinely curious if you would suggest that I request PEP after an incident I had on a weekend getaway.

• Took PrEP for 30 days, the hospital messed up with the scheduling had to stop for 10 days.
• Then last week Sunday through Thursday (5 days total) I took one Prep pill a day.
• Went on a trip on Friday and I forgot my pills, so I did not take any PrEP on Friday and Saturday.
  
• Sunday afternoon I had an incident where a guy was somewhat aggressively pushing it around my hole (butt) and then put the tip in for a second and I then told him to take it out and put on a condom and we did it with a condom. No ejaculation.
• Sunday midnight (I took another pill), Monday (another pill). I am back on track.

This is somewhat of a high risk individual who told me he wasn't on Prep. So I am a little conflicted by what I read online especially between the activity itself being low risk and a possible existing PrEP build up remaining etc.

My question: would you request PEP if you were me? Or do you think it would be unnecessary in this case.

I understand this shouldn't replace a medical advice.

This is my first round of Lenacapavir shots. It’s been almost 2 weeks and the bumps are still very pronounced outward. It makes me quite insecure about wearing crop top or anything that shows my stomach. 🥲💔The biggest bump on the right side feels kinda itchy and it’s more obvious than the first week. I don’t know. I’m still tracking my progress. It hurts!!! Very sensitive to the touch. Can’t lay on my stomach at all. I hope it will dissolve and become less obvious. It’s a hard lump. I hate it. I might go back to taking Truvada 😭🥲

Just for more info
I’m 24 yrs old. Quite skinny.
5’3” and 107 lbs.
Transwoman
Los Angeles, CA

My insurance covers everything! Talk to your PCP about it!!!!!

Update**** I feel much better today and the redness and the nodule size decreased after putting ice on them for about 30 minutes before I go to bed

Hi everyone!

I wanted to share my experience with Yeztugo (lenacapavir) after receiving my initial dose this past Monday 10/19/26 afternoon. I’m hoping to hear from others who have started this medication, particularly those who have experienced injection-site nodules.

After navigating a lengthy insurance authorization process that took nearly two months, I was finally able to receive my first dose. As part of the initial regimen, I received two subcutaneous injections in my abdominal area, along with the four oral tablets required for initiation.

The good news is that I haven’t experienced any systemic side effects. No nausea, fatigue, headaches, or other noticeable symptoms. Overall, I’ve tolerated the medication very well.
However, shortly after receiving the injections, I developed two fairly large, firm nodules at the injection sites. They are noticeable even without touching the area, and I can clearly feel the lumps beneath my skin.

I understand that injection-site nodules are a known side effect of Yeztugo, particularly because lenacapavir is a long-acting medication designed to remain in the body and provide sustained HIV prevention over six months.

My biggest concern is whether these nodules will eventually disappear or remain visible for an extended period.
Although the nodules aren’t particularly painful, their size and visibility have made me somewhat self-conscious. I’m also concerned about the possibility of developing additional nodules with subsequent injections.
I know that Yeztugo can be administered in either the abdomen or thighs, and I chose the abdominal area for my initial dose. I’m now wondering whether choosing the thighs for future injections might make a difference.

I was genuinely excited about getting a twice-yearly injectable PrEP option, especially considering the convenience and effectiveness of this medication. However, this experience has made me reconsider whether I would want to receive my next dose in six months.

For those who have received Yeztugo / lenacapavir injections, I have a few questions:

1. Did you develop noticeable lumps or nodules at the injection sites?
   If so, how long did they take to decrease in size or disappear?
   
2. Did your nodules eventually resolve completely, or can you still feel them months later?
   
3. Has anyone received injections in the thighs instead of the abdomen? Was your experience different?
   
4. Did you notice fewer or smaller nodules after subsequent injections?

I’m particularly interested in hearing from people who participated in the clinical trials and may have longer-term experience with lenacapavir.
I recognize that injection-site reactions are generally considered manageable, and I appreciate the tremendous advancement that Yeztugo represents in HIV prevention. Nevertheless, I think it’s important to discuss the patient experience, including cosmetic concerns and how these side effects may influence someone’s willingness to continue treatment.

As a health administrator myself, I’m especially interested in learning about the real-world patient experience with Yeztugo. Understanding how injection-site reactions affect comfort, appearance, satisfaction, and willingness to continue treatment can help inform patient education, care delivery, and support for others considering this twice-yearly PrEP option.

I’m hoping the nodules gradually decrease in size over the coming weeks or months.

I’d really appreciate hearing about your experiences, especially whether these lumps eventually went away.

Thank you everyone!

Hi all,

Long story short I’m going overseas and plan on having some intimate encounters. Had all the tests done and bought the drug…… been researching like crazy and says only 1 in 100 get side effects?? Does this sound about right??

I’m leaving Friday next week and don’t want to have any issues.

If I get bad side effects and stop the drug do the side effects go away rather quickly??

Thanks

Wanted to share my experience having an adverse reaction to yeztugo. The "medicine" did something to my skin. Hard to describe so this is what my plastic surgeon had to cut out of me due to the yeztugo injection. I attemped to have these removed via liposuction first, but it was not successful.

I took PrEP continuously for 9 days, then 9th day I had insertive vaginal sex with a women, but the condom got stuck at the end when I finished and pulled out. Do I need PEP ,because PrEP is not well defined for insertive vaginal sex . I am continuing to take my PrEP, am I good or no?

I started taking truvada about six weeks ago and ever since then I’ve had a cough. It used to be mostly a dry cough. I went to urgent care and they prescribed me bronchitis meds and I told them I was on truvada and they said it shouldn’t matter.

My dry cough has turned into a productive phlegm cough , which I think is what one of the medicines were for. However I ran the course of all the meds they gave me and it never seemed to help or go away. It just occurred to me that the cough could be related to the truvada. I stopped taking it today and am going to refrain from sex for a little while and see if my cough clears up.

Does anyone have any experience or advice with these similar symptoms? Thank you!

Wasted a month trying to get PrEP and Doxy PEP. First their home testing kit lancets don't work, and everyone I spoke to on the phone afterwards was already aware of the issue, and then they never filled the lab appointment because they waited until a day before and their system for working with Quest went down.

Find another service, don't use MISTR.

Context:

Have sex this afternoon, got bred twice and experimented some pee in the anus too. Used a plug so it’s overfilling already.

Around 6:15 I had a stomach feeling so I went to the toilet and it’s similar to number 2 but they’re all very liquid stool. (Similar to diarrhea but understandable given the liquids in me..?)

Then around 7 I guess I pushed more liquid stool out - less volume and amount but similar scent and texture.

I am on daily prep and took the prep at 7:15. But shortly after around 8 pm, I pushed out more liquid stool.

I’m not sure if diarrhea affects the absorption of prep? And in this case do I need to take one again?

So I just started taking prep/doxy, and I’m trying to figure out when I should be taking it. Are the side effects very prevalent and if so, is there merit to taking my prep before bed to sleep through those or am I worried about something that likely won’t matter? Also, I am prone to migraines, and the doctors I talked to said they didn’t know if prep would affect that, but does anyone in the same boat have any experiences that could help?

I’ve recently had my second round of Yeztugo and I wanted to address the leakage that comes from the injection sites.

My first round was in my belly and I’m a bit chubby, so things should have been fine. But my left side injection leaked quite a bit. The Dr. said it was expected and would be fine. I was still concerned and didn’t want the meds staining my shirts, so I came up with a fix.

For the second round of injections I had them placed in my belly, same place as last time. But this time instead of using their typical gauze and bandaid I used a Tegaderm film. This is the adhesive cover used in IV situations to stabilize the needle and prevent infection at the IV site. I do shave my belly smooth, and that makes the film stick much better.

I can report absolutely zero leakage and the bandages were so easy to wear under my shirt that I kept them on for two days😁

You can get Tegaderm patches on online shopping sites. I’d love to hear if your results are the same as mine🥰

I joined this group yesterday. Reading the comments from the folk that had bad experiences with this injectable I got a bit nervous. I had my first shots today. I took my loading dose pills. I didn't even feel the shots. I have the two nodules but I have absolutely no irritation or pain 6 hours after the shots. I was talking to the nurse today. She said that usually the people that experience pain is because they have low body fat. She told me they've never had somebody come back with ulcerated lesions or long-term problems other than leaking from the site. They have to get re-injected but that is rare. I suspect some of these problems are from faulty administration. This lady has done a lot of these shots! The clinic I go to serves almost all the LGBT population In my city. My pancreas does not like Truvada. I am so so glad that I don't have to do on demand prep anymore, which was the only way I could do this before. Every time I found a good hookup I would take my two pills and set something up for next day. Something would happen and I wouldn't be able to hook up! It was the most frustrating thing. It was so bad I had given up on sex! I will never go back to those darn pills.

Hi guys, I was taking Truvada for a while and noticed that it would give me terrible brain fog, depression and make me have lighter sleep and vivid dreams.

I’m thinking of switching to Yeztugo and wondering if anyone has made the switch and found that it doesn’t affect their sleep? Curious to know if you had any side effects following the injection as it stays in your system for a while and want to be sure it’ll be ok.

Stay safe everyone!

Hi all,

The prep I take is Teva Emtricitabine/Tenofovir Disoproxil. It’s in a blister pack.

I’ve been storing it in my nightstand since I got it. The weathers been cold here recently and I’m worried the indoor temperature might’ve been as low as 5 or 10 degrees at times.

The leaflet for my prep just says to keep it below 30 and it doesn’t give a minimum. But I see some websites online say it needs to be kept above 15 degrees.

Is mine ineffective? Do I need to find a new place to keep them or heat up my room?

I just started taking prep last Friday and have taken a pill everyday since. I know the time window for on demand prep is super strict but how is the time window for daily prep? I don't take it at the exact same time, but I take my daily pill from between 11am - 12. So I take the pill within that same one hour period everyday. I'm just paranoid because I just started it and I want to take it correctly. Do I have to take it at the exact same time everyday or is it okay to be within an hour window like this. I just want to make sure I'm protected. I researched on some websites that you're fine within 12 hours but I would never wait that long anyway.

I'm currently a SW, and have been trying to go on prep... Waiting for the medicine to be shipped to my medical office. I did request Yeztugo instead of the daily pill, bc I will forget. This has been quite the dragged out process. I requested the med over two weeks ago 😔

I wanted to see if there were other people who are SW and on Prep? I currently have 4 "sugar daddies", but when you boil it down, it's literally just SW, nothing more than sexual encounters. I want to protect myself because I do not trust that I'm the only person they're sleeping with. I'd rather be protected than not.

For reference I'm late 30s female, I'm also on tirzepitide, have an IUD, on Lexapro and have acid reflux.

Are there crazy side effects anyone's experienced while on GLPs or Lexapro?

I hope this post isn't taken down either.

Hi all,

The weather has been quite cold over the past few days here and I haven’t turned on my heating yet. As a result, my bedroom where I store my prep has been quite cold.

Could this have damaged my tablets and made them less effective? They are in a blister pack. The booklet inside the box just says to store below 30 degrees. It doesn’t give a minimum temperature but I see some sites online say it should be stored at at least 15 degrees. I think my room temperature was below that.

Hello, how is everyone doing? I have been using prep as on-demand and I am planning to stop using prep, no more fun, time to settle down lol, how long do i have to wait to get tested for an inclusive result? 45 or 90 days? Today has been 45 days since my last pill