r/prep • u/Sad-Orange-5983 • 8d ago

Could storing Prep in too cold a temperature damage it?

Hi all,

The weather has been quite cold over the past few days here and I haven’t turned on my heating yet. As a result, my bedroom where I store my prep has been quite cold.

Could this have damaged my tablets and made them less effective? They are in a blister pack. The booklet inside the box just says to store below 30 degrees. It doesn’t give a minimum temperature but I see some sites online say it should be stored at at least 15 degrees. I think my room temperature was below that.

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u/Skycbs 8d ago

How cold has it been?

You should never refrigerate PrEP since doing so may cause condensation, which certainly can damage the medication.

Here’s Gilead’s detailed storage information: https://www.askgileadmedical.com/docs/truvada-prep/truvada-storage-and-stability

As you can see, it’s unlikely you have a problem.

2

u/Sad-Orange-5983 8d ago

I doubt the room would’ve ever gotten lower than maybe 8 degrees. There was certainly no moisture or condensation on it.

1

u/Scar_Frank 7d ago

I might have left my pack on a shelf with contacts with sunlight, now I am scared the prep I used was damaged by an increase of temperature :(

1

u/Skycbs 7d ago

As the document I posted above says, brief temperature excursions are not a concern.