r/FTMdiyhrt • • 11d ago

Do not recommend 50mg unless OP has a low body weight.

48 Upvotes

Starters, 50mg is a low dose. It's not standard even in non-randomized studies, the standard for men obtaining a range of 350-650 ng/dL trough is 75mg.

50mg also will not suppress the ovaries/gonads. No study has shown consistent gonadal suppression in patients taking 50mg. Since we know it's notably harder to supress the gonads in tms, 50mg really just won't cut it. Whereas studies on 100mg has consistently shown it's efficiency in men.

Gonadal suppression is important for two reasons, prevention of pelvic pain and assuring the female reproductive system isn't functioning in males. If the ovaries are working, the uterus is working, causing it to continue functioning under partial suppression thus resulting in pain.

The best way to avoid pelvic pain is to maintain testosterone levels high enough to suppress the gonads and take aromatase inhibitors as needed to push estradiol levels into male range. This will assure full cessation.

As for masculinization efficiency, it’s been shown in Bhasin 2001, a study consisting of five dosage cohorts, each taking 25mg, 50mg, 125mg, 300mg or 600mg of Testosterone Enanthate. That men who took 25mg or 50mg weekly had significant decreases in testosterone compared to baseline. Specifically, to serum testosterone levels of around 300 ng/dL, hypogonadal levels of testosterone.

As a result, they displayed traditional signs of hypogonadism like increased body fat and lack of ability to increase muscle volume and muscle mass. Whereas in the 125mg cohort (570 ± 75 ng/dL), their body fat maintained alongside a significant increase in muscle volume and mass. In the 300mg cohort (1,345 ± 139 ng/dL) changes similar to the 125mg cohort occurred, however more drastic, alongside an increase in strength and IGF-1.

Read these articles for the list of studies and more detail. This is heavily summarized.

https://hrt4.me/articles/guides/male/#recommended-regimens

https://hrt4.me/library/androgens/tm-dosing/

A vast majority of everything I write is supported, my goal is to eventually add more citations.

Edit: I'm writing this as a reminder to rewrite stuff on Sustanon and write about how bad gel is.


r/FTMdiyhrt • • Jan 21 '26

Temporary Soreness, Redness and Hard Bumps Are Normal

67 Upvotes

I noticed I'm seeing a lot of hysteria regarding symptoms with injections that are actually normal and should be expected to a degree. So I want to make a pinned announcement to hopefully prevent misinformation and redundant posts.

Starters, testosterone vials are sustained in thick oils. At room temperature, the viscosity can go all the way from 27-33 cP to 1000-1500 cP all depending on the carrier oil used. The impact this has on the pharmaceutical's pharmacokinetics can be incredibly significant, take castor oil for example. (Source 1) (Source 2) (Source 3)

With that said, if you are injecting thick oils right underneath the skin (subcutaneous injections) you should expect to see visible, itchy bumps that may last for days. These are called depots. This will not be as much of a common occurrence if you do intramuscular, since the oil will be deeper into the injected tissue. (Source 4)

If you experience redness, bleeding or soreness, please note this is also normal. When you are injecting, you can damage some blood vessels which will induce slight bruising (redness) and perhaps blood leaking through the injection site. (Source 5) (Source 6) (Source 7)

None of these sensations or events means you are allergic to the carrier oil. Which is incredibly rare since these oils are refined and lack the protein for our immune system to respond to anyways. Not only that, you probably already consume these oils on a casual basis within your diet especially in processed foods. (Source 8)

However, if you experience unusual discoloring like green or blue pigment you should be alarmed. This includes other characteristics such as unusually large bumps, leaking pus, long-lasting side effects or immense pain. Which you'd then need to see a doctor for medical consultation, because likely that is an infection.

Edit: if you have various discolored/light/tanned bumps bunched around eachother in a large area, go to the ER immediately.


r/FTMdiyhrt • • 10h ago

is it normal to not get increased libido on T?

8 Upvotes

ive been on T for almost 3 months doing 60mg of test c. i haven't had any libido increase like people normally get. i cant get access to blood tests yet as i need to find a new gp and register to one that will do my blood tests, as my current gp straight up refused. is this a sign my T could be low? or is this a common thing


r/FTMdiyhrt • • 11h ago

might be underdosed

3 Upvotes

I'm taking trimonthly injections of 500mg and I just now realised it might be the same as taking 41mg per week which is low. I'm short and don't weigh much (159cm, 45kg). I also just got my blood test results and my test levels are just 2.6, and i started at 1.6. It was working really well on the first month and I even lost my period (although my period has always been quite weak and short) until late on the second month but I also haven't had any bottom growth literally AT ALL which I'm only really worried about since people often say that's the first thing they get. I'm mainly just wondering if it's normal to be so low since this was my first injection or if I should start DIYing.


r/FTMdiyhrt • • 21h ago

Do I really have to discard the vial after 4 weeks?

3 Upvotes

Been considering DIY for a bit, and a 10ml vial has a enough testosterone for a year. All sources say you have to discard it after 4 weeks, but is this really true, if the testosterone looks good and I keep everything sanitary?


r/FTMdiyhrt • • 1d ago

Any info on T cream?

3 Upvotes

Does anyone have any experience with testosterone cream(not gel)? I'm tired of the injection prep and the anxiety, and I can only get access to cream, so does anyone have any information on it? Also, this'll only be temporary since I'll be able to actually get prescribed next year. Anything would help..🥹


r/FTMdiyhrt • • 1d ago

Persistent period

3 Upvotes

I’ve been on t for about 6 weeks or so and for about a week and a half I’ve had my period. Doesnt seem so concerning, but I have a background w this.
When I was young, I had a period lasting from Christmas 2021 to around March 2023, only stopped after I started taking birth control. Would stop occasionally, I’d call them “reverse periods”, where I’d bleed for a month and occasionally stop for a little less than a week.
Back then, they were much heavier, but I’m still concerned that it could happen again.

Any similar experiences?


r/FTMdiyhrt • • 2d ago

Considering DIY

23 Upvotes

So I’m 13, I’m out to my parents as queer but not trans yet, and I’ve been considering DIY since I was 11. I’ll probably wait until I’m 15 or older, but I was wondering if I could hide side effects and if there are any repercussions of attempting to buy it in a small town in Texas? I know this also sounds silly, but I’m diagnosed with PCOS and hyperandrogenism, and was wondering if I could pull the “I’ve always been like this” card? Since I already have high levels of testosterone, I’ll just say it got worse? 😭 probably won’t work but maybe?


r/FTMdiyhrt • • 2d ago

Getting bitcoin under 18?

3 Upvotes

How do you get around getting bitcoin without your parents knowing under 18? I have the money but atms require you to be 18 and my bank account is one of those parent monitored ones where they see all my transactions. Is there any way to get around this or am i screwed


r/FTMdiyhrt • • 2d ago

underdosed/possibly bunk vial

6 Upvotes

I'd been diy'ing on pharma test e for 5-ish months (75mg weekly) and had been getting observable results (breasts shrinking, body hair, bottom growth, cessation of menses etc.) Eventually it ran out. I ordered from the same source but bought ugl this time due to it being cheaper and have been using it for a little short of 2 months. However, I've noticed conspicious shrinkage in bottom growth and slight swelling in breast tissue. I may be imagining this but my voice also feels lighter. No spotting yet but I'm afraid it may lead there if I don't do something about it. What I'm wondering is what should I be doing from now on. The source I bought both of these from had been recommended to me by someone who'd shown consistent results, both of the products had good reviews and the ugl one had lab test results cited (240mg/ml). I'm very unexperienced with ugl unfortunately, is it not uncommon for vials to be improperly dosed? Does it mean there's even a little test in the vial if I've gone 7 weeks without super drastic changes? I'd bought 3 ugl vials in total, should I try the other vials or something? I raised my dose to (what I assume is) 100mg the last shot I did 2 days ago just to see if it helps. I'd be grateful if someone could offer any sort of insight.

Edit: Forgot to include in post but I can't get bloodwork done.


r/FTMdiyhrt • • 2d ago

Parent is suspicious of me

10 Upvotes

Hi,
I’m 16 and I’ve been on T since the end of June. I stopped a bit in September, with the hopes of getting on prescribed T but I’m back again. My mom is suspicious because I kind of leave the bandage from my shot , and I guess she saw it on my stomach. She’s a nurse lol.
Thing is, I’ve talked to her about wanting to start hormones and I’ve been sending her stuff like planned parenthood and asked her to look at it. But I know these things are slow, so I just decided to start again.
Additionally, since I’m 16, even though my parents are divorced I do believe my dad would have to consent to hrt. And he’s just probably not going to. He’s barely agreed to sign my name change form (hasn’t done it yet btw—but I’m not too worried since even if he doesn’t the court doesn’t have to listen to him)
Anyway, I guess idk what to do since she’s sus. Should I tell her? Or should I let her eventually find out?
My voice has already dropped and I have body hair. Haven’t had my period since like July but I did lie about that to a doctor in front of her.


r/FTMdiyhrt • • 2d ago

Question about dosage/should I increase?

3 Upvotes

I suck at wording things over text so I apologize in advance. I’m 16 and I’ve been on DIY 1.2% Androgel for a year now, I currently do 60mg per day but I’m thinking about increasing my dosage as I’m worried 60mg isn’t enough (I still have a consistent menstrual cycle and I don’t feel like I look masculine enough for one year on T). I started on 40mg and last time I had blood work done my total testosterone levels were at 266, which is why I increased to 60mg in June. I haven’t got blood work done since going up to 60mg as the hospital I was going to got bought by a Catholic hospital and they won’t really help me more with transitioning related things due to that, for personal reasons I also cannot see another doctor at the moment to get blood work. So is it safe/worth the risk for me to increase to 80mg without getting blood work done again? Also my hematocrit was 42 back when I was on 40mg so is that something I should be concerned about if I do increase dosage? (No idea if this makes a difference too but I’m 5’7.3 and like 134lbs)


r/FTMdiyhrt • • 2d ago

how long would a 5g gel bottle last?

4 Upvotes

looking into starting on testoheal gel but dont know how often id need to buy. also wondering why application area matters


r/FTMdiyhrt • • 3d ago

Is it ok to be allergic to your testosterone?

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3 Upvotes

r/FTMdiyhrt • • 3d ago

How long does it usually take for a package to arrive?

1 Upvotes

I don‘t know if you can also trace a package or get updates from the sellers so I‘m pretty clueless when to expect the package


r/FTMdiyhrt • • 4d ago

Is it possible/efficient to up my prescribed dose slightly by taking DIY alongside it? Or is it better to go full DIY?

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1 Upvotes

r/FTMdiyhrt • • 5d ago

is this the right needle?

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6 Upvotes

r/FTMdiyhrt • • 5d ago

TGuys, how much are you injecting?

5 Upvotes

​

cypionate has arrived, the needles will arrive tomorrow and I will switch to injections. Kick-ass is exciting. I honestly did not understand how to choose the dosage (In my country, gender transition is prohibited by law, so I can’t ask an endocrinologist.). I plan to inject 250mg and take tests in 10 days, then after five days (??) I will put another 250 for two months on tst. by the way, I want to be happy, my voice changed quite quickly pn adrogel))I hope it continues to go the same way, because I started getting a hoarse voice, like in teenage boys, in week 4weeks, even though I missed quite a few doses.

But I’m afraid of overdoing it, so that everything doesn’t get converted into estrogen and there aren’t too many swelling. Tell me what medication you’re using, how often you take it, and how many doses you give. You can also share your experience in finding the right dosage — it would be interesting to read about too :)

sorry if there are mistakes, I use translator


r/FTMdiyhrt • • 5d ago

T shot anxiety

3 Upvotes

I’m around 8 weeks on T and honestly my injection anxiety has been increasingly worse as time has gone on. My first time was a little stressful but i was excited and it went well. A couple of times I’ve fucked up with z-tracking and my leg has bled a bit which scared me but I just had bad bruises for a couple of weeks. I keep trying to reassure myself by watching videos of trt injections and looking at diagrams of intramuscular injections but every week it’s worse. It can take like 2 hours for me to get to the point where I can actually inject myself.

For me it’s not the pain at all, it’s more risk of nerve damage/ hitting a vein. I’m very aware that the chances of these risks are extremely low but when I’m about to put the needle in the risks feel very high.

Anyone else struggle with this? Any advice is very appreciated. Thank you


r/FTMdiyhrt • • 6d ago

Can I keep using the same vial for 6 months

5 Upvotes

I recently learned you should change vials every month, and at most 3 months. I can’t afford to do that. Is it ok to at least use the same vial for 6 months


r/FTMdiyhrt • • 6d ago

Need advice on T levels

2 Upvotes

Hey people,

So I've been on DIY hrt for 4 months.

I've been taking a 100mg depot injection once a week.

It's a T enanthate & propionate combo called Testoviron Depot 100.

The last time I checked my levels:

Testosterone at trough: 500 ng/dL

Testosterone at peak: 1001 ng/dL

Estrogen (tested at same time as T peak): 111 pg/mL

Based on my reading and understanding:

T at trough seems good.

But are my T levels at peak too high?

Also is my estrogen too high? I am worried about aromatization.

Also, my periods had already stopped by month 3. But right now at month 4, I'm feeling symptoms of periods like abdomen cramps, tiredness and terrible mood. Which is what made me suspect the aromatization, so I got my estrogen levels checked.

The other culprit could also be the emergency contraceptive pill I took a few weeks ago. Consequences of unplanned unprotected sex.

So I'm trying to figure out what to do next. Would really appreciate any and all advice.


r/FTMdiyhrt • • 7d ago

will this T still be good?

5 Upvotes

i just bought a new T vial, but the manufacture date is 2024, and says the exp is 2029. i thought that T had a max shelf life of 3 years ?? im just a little skeptical. would it still be okay to use it ?


r/FTMdiyhrt • • 7d ago

Really scared I injected wrong

8 Upvotes

Got a new vial and got it ready like usual and tried to inject. First time I couldn't make it all the way in, it felt like something was blocking me so I pulled out. Second time felt really painful and it was just the top. Third time I made sure I did it in the correct area (I do IM) and after pulling out it bled

It wasn't a drop of blood, it was a long line of red. No soreness or pain. Did I hit something? Did the testosterone bleed out (???) Sorry I'm pretty worried


r/FTMdiyhrt • • 8d ago

Dosing help?

5 Upvotes

I'm 16 and pretty underweight. Like 40-45kg if I had to guess. I need to get my new blood test since the one I bought just didn't work? So I can see my natural T levels since I'm starting DIY hrt but I'd like some advice or help? All help is appreciated :D


r/FTMdiyhrt • • 8d ago

Dosage help

3 Upvotes

Hi, I have been doing IM 50mg once a week (have been on T for 3 weeks so far, in two days it will be my 4th). I'm planning to start doing subq come my 4th shot however, and since it is a different delivery method, should I wait and keep doing 50mg for say 2/3 weeks and then up it to 75mg? Or is that not required?