r/LowDoseNaltrexone • u/Volavons • 21h ago

Brain inflammation

Ok so I've always unfortunately had OCD, Tics, Anxiety and other things because of my autism but they were manageable and could go months without bothering me.

Since getting long covid and mcas they've rapidly gotten worse which could be due to brain inflammation, dopamine block from the LC or maybe nervous system deregulation.

Could LDN potentially be helpful here? I also have pain, fatigue and all the typical MCAs and LC issues.

I've been on 0.2mg for two weeks. So far I got a bit more depressed than usual, sleep got shit quality wise and my tics have gotten worse.

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2

u/chikitty87 10h ago

Yes this relates to histamine and LDN can help with histamine.
Have you tried anti-histamines? MSM? Thiamine supplementation? Last two actually can HEAL things, LDN and anti-histamines are just managing tools

1

u/Volavons 9h ago

I have fexofenadine, famotadine and ketotifen for anti histamines

Msm I think I tried once and didn't react great same with b1 I know it can really mess with you

4

u/Successful-Basis-145 19h ago

According to the LDN Research Trust LDN can help with all your symptoms but it takes time and in the beginning it can get worse before getting better.

1

u/lolalanabanana 15h ago

Gets worse every time you go up a bit , it’s a slow titration so you need to give it at least 6mo before you draw any conclusions. You’ve been on it for 3 seconds ofc it’s not working yet